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OSSC Annual Business Meeting and Talk by Alex Small (Cal Poly)
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Category
OSSC Regular Meeting
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About this event
Annual Business Meeting, Election Results, and Presentation on:
What is superresolution microscopy, how far can it go, and why did your professor mislead you?
Abstract: Most of us heard in college that because of the diffraction limit it is impossible for an optical instrument to image structural details smaller than the wavelength of light. However, the 21st century has seen astounding advances in superresolution fluorescence microscopy techniques. While there are several different approaches to the concept of superresolution, what they all share in common is an ability to exert molecular-scale control over the state of a fluorescent molecule. Consequently, while the lenses and cameras continue to form diffraction-limited focal spots, by combining information on how the state of the molecule was controlled with clever image processing algorithms, we can image cells down to the single-molecule scale, enabling imaging that was considered impossible in the not-too-distant past. Some of the most exciting applications of this work are in the biomedical sciences, but the basic principles are all about physics and statistics, not biology, and can be applied to a wide variety of imaging situations. In this presentation I will explain the principles underlying the various superresolution techniques, and also the fundamental limits that have replaced Abbe’s diffraction limit.
Wednesday, 14 June, 2017
Reception: 6:00
Dinner: 7:00
Business meeting and talk: 7:45pm
Meal $35 for registration by 11 June, $45 for registration after
$10 for OSSC student members who register by 11 June, $20 for student members who register after
Please Register by Sunday, 11 June, 2017
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